Introduction to Oncology Laboratory
Oncology laboratory is a key department covering experimental diagnosis, scientific research and teaching in tumor. It is now the "Key Laboratory of Tumor Metastasis and Individualized Diagnosis and Treatment Transformation Research", and " Individualized Cancer Drug Testing Collaborative Innovation Center" in Chongqing, and is also the graduates training base and postdoctoral research workstation of Chongqing University, Chongqing Medical University , as well as the base for the "Academician Workstation" . Focusing on "Precision Diagnosis and Clinical Transformation of Tumor", the laboratory strengthens discipline construction, focuses on tumor genomics, real-time liquid biopsy, tumor intelligent medicine, applies mass spectrometry, flow cytometry, biochip and gene sequencing and other new technologies to carry out basic and clinical transformation research of tumor, detection of circulating tumor cells, immune cells and cellular causes. It provides technical platform and intellectual support for cancer screening and early warning, early diagnosis, treatment evaluation, recurrence and metastasis monitoring and prognosis judgment in Chongqing.
At present, there are 11 faculty members in the laboratory, 2 with doctor’s degree and 4 with master’s degree, among whom there are 2 tieh senior positions and 4 intermediates. There is another postdoctoral student in the station, and 5 members completing various projects. At present, the team focuses on three directions:
1. Cancer genomics, focusing on cancer gene detection to achieve individualized drug use, and drug genome analysis, blood drug concentration detection, specific tumor marker screening, etc.
2. Intelligent medical technology, focusing on the intelligent medical technology, clinical image analysis, clinical digital system and other aspects. It applies advanced computer information technology such as artificial intelligence and edge computing to the field of clinical disease morphology test, develops the automatic interpretation system and expert diagnosis system of clinical test morphology based on the in-depth learning of artificial intelligence, and promotes the digitalization, intelligentialization, and standardization of clinical morphology testing technology.
3. Liquid biopsy technology, aiming at early diagnosis and screening of tumors, focusing on imRNA, cfDNA, exosomes and circulating tumor cells, and seeking technical transformation and clinical application by means of engineering methods such as microfluidic technology and photoelectric technology.
The Department consists of six professional laboratory platforms: Foundation Lab, Cell Biology Lab, Mass Spectrometry Analysis Lab, Radiation Biology Lab, Flow Cytometry Lab, and Precision Instrument Lab, equipped with a series of advanced instruments and equipment such as Japan's Olympus living cell workstation, Germany's cellcut CellEcto suspension single cell selection and laser cutting system, America's precision x-rad 225 irradiator, BD flow cytometer, real-time fluorescent quantitative PCR, flow cytometer, Thermo TSQ Endura triple quadrupole liquid mass spectrometer, fluorescence microscope, cell incubator, low temperature (- 85 ℃) refrigerator, etc. In recent years, the department has undertaken and completed more than 20 scientific research projects and applied for and authorized more than 10 invention patents. The department has also published more than 50 academic papers in domestic and foreign journals.